hours due to its active metabolites. Parke-Davis Div of Pfizer Inc. https://www.drugs.com/pro/lipitor.html. Medicines that interact with Lipitor may either decrease its effect, affect how long it works for, increase side effects, or have less of an effect when taken with Lipitor. Take once daily. Data sources include IBM Watson Micromedex (updated 2 Nov 2020), Cerner Multum™ (updated 2 Nov 2020), ASHP (updated 23 Oct 2020) and others. Medically reviewed by Carmen Fookes, BPharm. Common medications that may interact with Lipitor include: Note that this list is not all-inclusive and includes only common medications that may interact with Lipitor. Try to avoid second-hand smoke. Copyright 1996-2020 Drugs.com. Last updated on Jun 11, 2020. Take Lipitor exactly as directed by your doctor. These symptoms typically resolve with discontinuation. and would therefore diminish its effect. LIPITOR is for adults and children over aged 10 years whose cholesterol does not come down enough with exercise and a low-fat diet alone. "how long does it take for lipitor (atorvastatin) to lower cholesterol?" activity of Lipitor. package insert, one study showed that drinking one glass of grapefruit Lipitor is available as a generic under the name atorvastatin. How long does it typically take for cholesterol to begin reducing?" Lipitor starts to lower cholesterol within about two weeks of starting the medication. May be taken at any time of the day (morning or night); however, it is best to be consistent with the time you take Lipitor. desired effect. Lipitor, in conjunction with dietary measures, may be used for the treatment of high cholesterol in people at increased risk of cardiovascular disease if initial dietary measures fail to lower cholesterol. Could my Lipitor be causing memory loss? increased drug concentrations 250%. CYP3A4. Lipitor is a brand (trade) name for atorvastatin. My doctor put me on Lipitor for cholesterol. If you take too much Lipitor or overdose, seek immediate medical care. Food may decrease the absorption, but does not seem to impact the reduction in cholesterol. known as an HMG-CoA reductase inhibitor. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Dr. Kevin Davis is a licensed pharmacist with experience in retail and hospital pharmacy. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Avoid drinking large quantities of grapefruit juice or eating grapefruit or grapefruit products while taking Lipitor. Adhere to the TLC diet, designed by the National Cholesterol Education Program (NCEP), or a similar diet, while taking Lipitor. side effects. Speak to your doctor about how drug interactions should be managed. and many HIV medications. Lipitor is a popular statin, or cholesterol-lowering medication. He graduated from the University of Florida with a Doctor of Pharmacy degree in 2015 and a Master of Healthcare Administration degree from Adventist University in 2017. People who need to use medications such as statins to lower their cholesterol should see their cholesterol levels fall quickly. Avoid grapefruit juice to avoid risk of This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Examples of CYP3A4 inhibitors include diltiazem, digoxin, grapefruit, Talk to your doctor to determine if this is appropriate for you. While the medication starts working within a few hours, it will probably take at least two weeks before any impact on cholesterol levels will be significant. How long does it take cholesterol to go down? In our latest question and answer, the pharmacist discusses how long it takes for Lipitor (atorvastatin) to begin working (i.e. Lipitor should not be taken during pregnancy or while breastfeeding. While many statins are recommended to be taken in the evening, Lipitor can be taken at any time of day. Muscle pain, tenderness, or weakness - initially needs further investigation to rule out more serious muscle effects (such as rhabdomyolysis - the destruction of muscle cells). But there are some Lipitor side effects you should be aware of before taking this drug. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. How long does it take to work? Atorvastatin belongs to a group of medicines called statins.. Atorvastatin may be used for the treatment of high cholesterol. may decrease the absorption, but does not seem to impact the reduction in cholesterol. May also affect some diabetes markers (such as HbA1c or fasting glucose), and may not be suitable in those with liver or kidney disease. of 37%. Lipitor should always be taken in conjunction with a diet to lower your cholesterol and … CYP3A4 inducers reduce the Atorvastatin works by blocking an enzyme in the liver that makes different types of lipids (fats and cholesterol). Plan to exercise regularly and stop smoking if you smoke. While many statins are recommended to be taken in the evening, Lipitor can be taken at any time of day. Answered by Dr. Luis Villaplana: Depends: Depends on your … It's used to lower cholesterol if you've been diagnosed with high blood cholesterol.It's also taken to prevent heart disease, including heart attacks and strokes.Your doctor may prescribe atorvastatin if you have a family history of heart disease, or a long-term health condition such as type 1 or type 2 diabetes or rheumatoid arthritis. Rarely, has been associated with memory loss, forgetfulness, amnesia, memory impairment, and confusion. of total cholesterol, LDL cholesterol (known as “bad” cholesterol), and Consider temporarily withholding Lipitor and seeking urgent medical advice if you have any acute muscle pain or another condition that may increase your risk of serious muscle injury or kidney failure such as a severe infection, major surgery, trauma, uncontrolled seizures, severe electrolyte or metabolic disorders. LIPITOR can be administered as a single dose at any time of the day, with or without food. Lipitor can be taken with or without food. American College of Lipitor has a half-life of about 14 hours, but continues to work for 20-30 May interact with a number of other medications including those metabolized by hepatic enzymes CYP 3A4, clarithromycin, protease inhibitors, cyclosporine, gemfibrozil, oral contraceptives, and digoxin. Select one or more newsletters to continue. Do I have to take my Lipitor at night as written by the doctor? Lipitor is effective at lowering cholesterol; however, its use may be limited by side effects such as muscle pain. Food An interaction between two medications does not always mean that you must stop taking one of the medications; however, sometimes it does. Per the Lipitor Possibly more effective than other statins. Lipitor, like other statins, may affect liver function, manifesting as changes in liver function tests or jaundice (yellowing of the skin) requiring dosage reduction or discontinuation. rhabdomyolysis. Cardiology and American Heart Association. Should you take Lipitor with or without food? I take all of my medications in the morning. Peak levels are seen within one to two hours following administration; however, it may take one to two weeks of regular dosing before improvements in your cholesterol level are seen, and up to four weeks before the maximal cholesterol-lowering effects of Lipitor are apparent. Patients who require a large reduction in LDL-C (more than 45%) may be started at 40 mg once daily. Lipitor is also used to lower the risk of coronary events (such as a heart attack or stroke) in patients at high risk of these events - such as people with pre-existing coronary heart disease, diabetes, peripheral vessel disease, a previous history of stroke and stroke-like events or heart attack, or with multiple risk factors (such as older age, smoking, high blood pressure, low HDL-C, and a family history of heart disease). Bottom Line. When Can I expect results? The most significant drug interactions See your doctor straight away if you notice any yellowing of your skin or shortness of breath, unexplained cough or general tiredness. be checked after 2-4 weeks. Lipitor is rapidly absorbed within about 1 or 2 hours. Lipitor belongs to the class of medicines known as statins. We comply with the HONcode standard for trustworthy health information -. You should refer to the prescribing information for Lipitor for a complete list of interactions. Are Statin Side Effects 'All in Your Head'? may lead to side effects like muscle pain and a severe condition known as CYP3A4, P-glycoprotein, and OATP1B1. Inducing the enzyme would cause rapid metabolism of the drug Atorvastatin also boosts the breakdown of lipids. Atorvastatin can reduce LDL levels by up to 45-60%.