Zetia side effects can be quite serious, especially in high doses. This bloatedness can cause for pseudo weight gain as well. You may report side effects to FDA at 1-800-FDA-1088. Find information about common, infrequent and rare side effects of Zetia Oral. Common Side Effects of Zetia. Symptoms reported are Myalgia and myopathy. I have had very good results following the diet in the Digest Diet book, put out by Reader's Digest. So, some people think this drug may have effects to gain weight. In these studies, side effects are always documented and compared to another group not taking the medicine. As per my analysis, don't skip doses. I Have used Generic Zetia 10 mg. there are no side effects. However, this fact is still under research. Zetia has been studied extensively in clinical trials, with more than 12,000 people having been evaluated. it is highly reactive. A natural alternative for lowering LDL cholesterol may be a much safer option for you and is worth exploring with your cardiologist. There are also good diets which dramatically affect your cholesterol levels. This is not a complete list of side effects and others may occur. Read More. There are many good drugs on the market which may not give you such severe side effects. SIDE EFFECTS FOR ZETIA: COMMENTS: SEX: AGE: DURATION/ DOSAGE: DATE ADDED : 1: Elevated LDL cholesterol: Headaches. They can include severe muscle pain and kidney damage, among other significant adverse reactions. Our Zetia Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication. Call your doctor for medical advice about side effects. Zetia Muscle Pain – Myalgia, Myopathy & Rhabdomyolosis . Upset stomach, backache, pain in knee joint, fatigue, nasal congestion. otherwise, it will hurt you. As well as many other side effects, one of the common reported side effects of zetia is muscle pain. Avoid alcohol after taking this drug. Hence, let’s wait until the experts announce whether this can cause weight gain and by that for diabetes. Until that, it’s better to be aware of keeping in mind about the risk. Zetia (ezetimibe) is a drug used in the treatment of high-cholesterol. Your healthcare provider can discuss a more complete list of Zetia side effects with you.) I too have had to resort to Zetia after side effects with all the others. Zetia Muscle pain is one among of its side effects.